1. Home
  2. Services
  3. SPRAVATO

Spravato®

First FDA-approved nasal spray proven to relieve symptoms of treatment-resistant depression (TRD).

Find out if Spravato® is Right for you Call Us

Spravato®

Depression is treatable, but standard therapies and medications don't help everyone. Dedicated to providing comprehensive, cutting-edge care, experienced psychiatrist Dinar Sajan, MD, and her team at Health & Psychiatry offer SPRAVATO® which is the first FDA approved nasal spray for treatment-resistant depression in adults.

If you've tried two or more antidepressants* without sufficient relief, contact one of our offices across Florida by phone, or you can request an appointment online today to see if you may have treatment-resistant depression.


Transforming Lives with NeuroStar TMS at Health & Psychiatry!

What is Spravato®?

SPRAVATO®, the first FDA-approved esketamine nasal spray medication specifically developed for adults with treatment-resistant depression or the depression that has not improved after trying at least two different antidepressants.

SPRAVATO® works by targeting the N-methyl-D-aspartate (NMDA) receptor in the brain, which is part of the glutamate system. This mechanism is different from traditional antidepressants that primarily affect serotonin, norepinephrine, or dopamine. By acting on the NMDA receptor, SPRAVATO help reset brain pathways involved in mood regulation, often leading to faster symptom improvement. Spravato is the only medication on the market that works through this pathway making it a truly unique experience.

Book an Appointment Call Us

Who Can Benefit from Spravato®

SPRAVATO® is prescribed alongside an oral antidepressant for adults who:

  • Have treatment-resistant depression (TRD): depression that hasn't improved after trying two or more antidepressants
  • OR
  • Experience depressive symptoms with suicidal ideation as part of major depressive disorder (MDD)

Before You Begin

Before beginning SPRAVATO®, patients should understand:

  • It is not a pain medication or anesthetic
  • It does not replace hospitalization if your provider determines inpatient care is necessary

Spravato Room at Health & Psychiatry

What to Expect During Your SPRAVATO® Treatment?

Spravato® is always administered under the direct supervision of a healthcare provider in a controlled clinical environment.

Click on these steps to review details.

  1. You will self-administer the nasal spray under provider guidance.
  2. Your blood pressure will be reassessed approximately 40 minutes after dosing and monitored as needed.
  3. You will remain in the office for at least two hours for observation, in accordance with national safety guidelines.

Patients spend this time in a quiet, low-stimulus environment. You may:

  1. Sit in a comfortable recliner
  2. Listen to music
  3. Watch a movie or use a device with headphones
  4. Rest, meditate, or simply relax

Many individuals find this time restorative and supportive to the overall treatment experience.

  1. Patients may drive to the appointment, but are not permitted to drive afterwards.
  2. A responsible adult, ride share, or arranged transportation must be used.
  3. Spravato® recommends avoiding driving until you have had a full night of sleep, even if you feel alert.

Side Effects and Safety
Information for SPRAVATO®

SPRAVATO® can cause serious side effects. It's important to understand what to expect and when to seek help.

Common Side Effects During Treatment

Sedation and Dissociation

Some patients experience sedation or dissociation during treatment, which may include:

  • Feeling sleepy, dizzy, or faint
  • Experiencing a spinning sensation
  • Feeling disconnected from yourself, your thoughts, or your surroundings

If you feel unable to stay awake or feel like you might pass out, inform your healthcare provider immediately.

Important Safety Considerations

Suicidal Thoughts and Behaviors

Like other antidepressants, SPRAVATO® may increase the risk of suicidal thoughts or actions, particularly in individuals under 24 years old during the first few months of treatment or when doses are adjusted. SPRAVATO® is not approved for use in children.

Blood Pressure and Cardiovascular Considerations

SPRAVATO® may temporarily increase blood pressure, which is why careful monitoring is required before, during, and after each treatment session.

Pregnancy

SPRAVATO® is not indicated for use during pregnancy and must be stopped immediately if pregnancy occurs.

Telepsychiatry:
Expert Care From Anywhere

Access expert personality disorder therapy from the comfort and privacy of your own home through secure, HIPAA-compliant video appointments.

You can meet with one of our licensed providers, including our experienced psychiatrist, using your smartphone, tablet, or computer.

  • Receive care from the comfort of your home
  • Eliminate travel time and transportation barriers
  • Flexible scheduling around work and family commitments
  • Maintain continuity of care even when traveling
  • Access to the same expert providers and personalized treatment
Schedule a Virtual Visit

What to Bring

Drivers license

1. Driver's License

Insurance Card

2. Insurance ID Card

prescription bottles

3. Prescription Bottles

Your Insurance Likely Covers Your Care

We accept most major insurance plans. Let's verify your coverage before your first visit.

AETNA
Alignment healthcare
baycare
blue cross shield
care plus
cigna
medicare
united healthcare
advent health
florida blue
carelon
devoted
florida complete care
freedom health
lucent health
magellan
US Tricare
Oscar
Sunshine health
Optimum healthcare
Check Accepted Insurance

Frequenctly Asked Questions

Have questions about tech tools, insurance, or session flow? You’re not alone. Explore our FAQs or contact support for any help before or during your virtual visit.

SPRAVATO® has shown positive results in many people with treatment-resistant depression. In clinical studies, some patients experienced significant improvement in their symptoms within the first few weeks of treatment. While results can vary, combining SPRAVATO® with an oral antidepressant has helped many people who haven’t responded to other medications. Your success with SPRAVATO® will depend on your individual health and how your body responds to the treatment.

SPRAVATO® is not approved specifically to treat anxiety, but if you have both treatment-resistant depression and anxiety, you may still benefit from it. Many people with depression also experience anxiety, and some report improvements in both symptoms during SPRAVATO® treatment. However, everyone responds differently, so it's important to talk to your doctor about your full symptoms. Your provider can help decide if SPRAVATO® is a good option for your situation.

SPRAVATO® may start working faster than traditional antidepressants. Some people begin to feel relief from depression symptoms within 24 hours of their first dose, especially if they are experiencing severe symptoms. However, response times can vary, and it may take a few sessions to notice a significant change. Your healthcare provider will monitor your progress and adjust your treatment plan as needed to get the best results.

You should not use SPRAVATO® if you have a history of bleeding in the brain (aneurysm), any type of brain injury, or uncontrolled high blood pressure. It is also not recommended if you have an allergy to esketamine or ketamine. SPRAVATO® is not approved for use in children or if you are pregnant or planning to become pregnant. It is also not intended to be used as a pain medication. Before starting treatment, your doctor will review your medical history to ensure SPRAVATO® is safe for you. Always share any health conditions or medications you are taking with your provider.

Most patients that experience sedation or dissociate compare it to feeling "tipsy" or similar to the feeling of "having a few glasses or wine". However monitoring is for two hours as most people feel back to their baseline or how an absence of these symptoms after one hour on average. Driving is not permitted after treatment as any impairment of reflexes could reduce a person ability to safely operate a vehicle. Not all patients experience these side effects.

Most facility the medication is administered by medical assistants that are not credentialed to make adjustments to psychiatric medications or Spravato treatment. At this facility a medical provider is directly assessing and evaluating treatment at each visit. If a patient is not responding appointments can be made during the visit without delay. Separate medication management and Spravato appointments are not required.

Confidence and Expertise
Built on a strong foundation of accredited compliance

HIPPA Compliance

HIPAA Compliance

We maintain full HIPAA compliance, ensuring all healthcare data is protected with the highest level of confidentiality.

SOC2

Type II SOC 2 Compliance

Being SOC 2 Type II certified highlights our commitment to rigorous security practices and safeguarding data integrity.

American Psychiatric Association

American Psychiatric Association

Works in coordination with the American Psychiatric Association

Start Your Treatment Now

Request an Appointment

Your journey toward making a lasting impact in mental health starts here. Fill out the form and discover how you can find hope and healing with Health & Psychiatry.